Basic Information
Introduction to Cellular Biomechanics Focusing On The Physical Basis Of Cell Mechanosensing# The Ability of Biological Cells to Sense And Respond to Elasticity and Mechanical Cues. Experimental Techniques And Theoretical Modeling (using Statistical Mechanics and Stochastic Processes) of Mechanics at The Nanoscale. Stress-induced Phase Transition in Lipid Membranes and Cytoskeleton Networks, Mechano-chemical Coupling# Coupling Between Force And Conformational Changes in Single Molecules and Bond Rupture Experimental Methods For Measuring Mechanical Forces and Deformations At The Nanoscale Including# Single Molecule Force Spectroscopy, Traction Force Microscopy (tfm) and Fluorescence Resonance Energy Transfer (fret) Sensors. Learning Outcomes# Upon Completion of This Course It Is Intended That The Student Will# 1. Understand The Difference Between Mechanical Behavior of Classical Systems And Mechanics of Self-assembly Systems (e.g. Biological Membranes And Acting Cytoskeleton). 2. Understand The Role of Stochasticity On The Single Molecule Level (for Cell Mechanosensors and Molecular Motors). 3. Know How to Derive Macroscopic Properties From Single Molecule Behavior. 4. Know How To Follow Simple Derivation of Statistical-mechanics Models in The Field. 5.have Gained Experience in Critical Reading of The Literature.
Faculty: Mechanical Engineering
|Graduate Studies
Pre-required courses
(34029 - Solid Mechanics 2 and 34035 - Thermodynamics 1)
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