Basic Information
Introduction to Controlled Drug Delivery# History, Basic Principles, Advantages/disadvantages, Limitations, Smart Drug Delivery Systems Motivation and Current State-of-the-art. Smart Drug Delivery Systems# Nano-based Systems, Stimuli-responsive Systems, Targete3d-systems, Carrier-free Systems. Cellular-based Systems and Theragnostic Systems. Smart Drug Delivery Systems Engineering# Smart Components/chemistries (phase Transition), Stimuli/suitable Smart Ddss (ph, Redox, Molecule-responsiveness Systems, Bio-responsive, , Light, Temperature, Magnetic, Ultrasound, Others). Smart Drug Delivery Systems Characterization# Chemical (composition And Functionality), Physical (size, Morphology and Distribution) And Thermal Analysis. Implants As Smart Drug Delivery Systems# Advances And Actively Moving Polymers. Systems Validation and Monitoring Models# Imaging, in Vitro and in Vivo (including Pk/pd Modeling (pharmacokinetic/pharmacodynamic Modeling). Smart Drug Delivery Systems Projects Discussion. Learning Outcomes# at The End of The Course The Students Will Be Able To# 1. Determine The Key Differences Between Regular Drug Delivery Systems (ddss) and Smart Ones. 2. Evaluate The Impact of The Varied Elements Needed to Be in The Ddss In Order to Convert Them to Advanced Smart Systems Including# Microstructures and Macrostructures Elements, Chemistries, Pk/pd And Mechanisms of Administration. 3. Differentiate Between The Vairded Smart Ddss Including Their Advantages and Limitations and Their Performance Methodology. _ 4. Discuss and Practice Suitability of Specific Smart Ddss For The Desired Applications.__ 5. Analyze The Correlation Between Chemical Structure and Properties Of Smart Ddss. 6. Analyze The Design, Synthesis and Application of Different Smart Material-based Delivery Systems._ 7. Determine Proper Analytical and Monitoring Tools For Smart Ddss.
Faculty: Chemical Engineering
|Undergraduate Studies
|Graduate Studies
Pre-required courses
(54350 - Polymers 1 and 124708 - Organic Chemistry 1/ Extended) or (54413 - Polymers and Applications in Biotechnol. and 125801 - Organic Chemistry)