Basic Information
This Course Will Cover Microfabrication Technologies, Originally Developed For Integrated Circuit Fabrication, and Their More Recent Applications in Healthcare and Biology. The Opening Lecture Will Provide an Introduction to Microfabrication and Microsystems# Photolithography, Etching, Evaporation, Sputter Coating, Oxidation, Etc. Two Classic Examples of Silicon Microsystems Will Follow# Pressure Sensors and Accelerometers. We Will Then Move On To Microfabrication For Healthcare and Biology and "soft Lithography" Techniques. Topics Will Include (1) Microelectrode Arrays (2) Microfluidics and Its Applications to Cell Biology, in Particular For Revolutionary Technologies Such As Cell Sorting and Single Cell Rna Sequencing, (3) Protein and Cell Micropatterning. Different Methodologies, Utility, and The Influence of Micropatterning On Cell Mechanics and Ultrastructure, (4) Measuring Cell Forces Using Traction Force Microscopy (tfm Is Basically Piv). Two Different Tfm Methods# Deformable Micropillars and Hydrogels With Fiducial Markers. (5) Biohybrid Materials For Building Actuators and Powering Devices. (6) Organ-on-a-chip. The Course Will Include Several Hands-on Experiments and Demonstrations to Deepen The Students Intuition. Learning Outcomes# at The End of The Course The Students Will Be Able To# 1. Understand Fundamental Processes in Microfabrication Such As Lithography, Thin Film Deposition, and Etching, As Well As Gain Familiarity With Broader Concepts Such As Batch Fabrication. 2. Widen Their Horizons By Delving Into Major Advances in Biology And Medicine Catalyzed By The Application of Microfabrication Techniques To Soft Materials Such As Polymers. 3. Demonstrate Basic Skills in Microfabrication Process Design And Developed Intuition Through In-class Demonstrations.
Faculty: Mechanical Engineering
|Graduate Studies
Pre-required courses
(34020 and 34053 - Solid Mechanics 2m)